PMSF

• UNSPSC Description:

  PMSF is an irreversible serine/cysteine protease inhibitor commonly used in the preparation of cell lysates.

• Target Antigen:

  Cathepsin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pmsf.html

• Purity:

  99.91

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL|Isopropyl alcohol : 60 mg/mL (ultrasonic)

• Smiles:

  O=S(CC1=CC=CC=C1)(F)=O

• Molecular Weight:

  174.19

• References & Citations:

  [1]Sekar, M.C. and B.D. Roufogalis, Differential effects of phenylmethanesulfonyl fluoride (PMSF) on carbachol and potassium stimulated phosphoinositide turnover and contraction in longitudinal smooth muscle of guinea pig ileum. Cell Calcium, 1984. 5(3): p.|[2]Guther, M.L., W.J. Masterson, and M.A. Ferguson, The effects of phenylmethylsulfonyl fluoride on inositol-acylation and fatty acid remodeling in African trypanosomes. J Biol Chem, 1994. 269(28): p. 18694-701.|[3]Compton, D.R. and B.R. Martin, The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. J Pharmacol Exp Ther, 1997. 283(3): p. 1138-43.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  329-98-6