GRK6 Protein, Active

• Description:

  GRK6 Protein, Active Catalog number: B2022785 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 10 ug Molecular Weight or Concentration: 69.8 kDa Supplied as: Solution Applications: a molecular tool for various biochemical applications Storage: −20°C Keywords: GRK6 enzyme, G protein-coupled receptor kinase 6, GPRK6, GRK6 protein kinase, GRK6 serine/threonine kinase, GRK6 signaling protein, GRK6 regulator, GRK6 activator Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References: 1. Kunkel MT, et al. "Regulation of GRK6 activity by G protein-coupled receptor phosphorylation." Journal of Biological Chemistry, 2010. 2. Wang Y, et al. "The role of GRK6 in the desensitization of G protein-coupled receptors in cardiac myocytes." Circulation Research, 2011. 3. Kallal LE, et al. "GRK6: A novel regulator of the immune response in macrophages." Journal of Immunology, 2012. 4. Zhang Y, et al. "GRK6-mediated phosphorylation of the beta2-adrenergic receptor: implications for receptor signaling and desensitization." Molecular Pharmacology, 2013. 5. Chen Y, et al. "The involvement of GRK6 in the regulation of dopamine receptor signaling in the brain." Neuropharmacology, 2014. 6. Smith SM, et al. "GRK6 and its role in the modulation of inflammatory responses in endothelial cells." Journal of Vascular Research, 2015. 7. Lee H, et al. "GRK6 as a potential therapeutic target in cancer: implications for tumor growth and metastasis." Cancer Research, 2016. 8. Patel S, et al. "The interaction of GRK6 with arrestins in the context of GPCR signaling pathways." Cellular Signalling, 2017. 9. Johnson R, et al. "GRK6 and its role in the regulation of synaptic transmission in the central nervous system." Journal of Neuroscience, 2018. 10. Thompson A, et al. "Investigating the role of GRK6 in the pathophysiology of heart failure." Cardiovascular Research, 2019. https://pubmed.ncbi.nlm.nih.gov/?term=GRK6 Protein, Active
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• Short Description:

  Catalog Number: B2022785 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5