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Desacetyl Forskolin

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Description
Deacetylforskolin is a deacetylated derivative of forskolin that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity.
CAS Number
64657-20-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
368.47
Molecular Formula
C20H32O6
Notes
Research use only, not for human use.
Receptor
Other Targets

Chemical Information

Deacetylforskolin

See also: Deacetylforskolin from Coleus forskohlii (annotation moved to).

CAS Number64657-20-1
PubChem CID10044542
IUPAC Name(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-1-one
Molecular FormulaC20H32O6
Molecular Weight368.5
XLogP0.4
Topological Polar Surface Area107
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Heavy Atom Count26
Formal Charge0
Complexity646
SMILES
C[C@@]1(CC(=O)[C@@]2([C@]3([C@H](CCC([C@@H]3[C@@H]([C@@H]([C@]2(O1)C)O)O)(C)C)O)C)O)C=C
InChI
InChI=1S/C20H32O6/c1-7-17(4)10-12(22)20(25)18(5)11(21)8-9-16(2,3)14(18)13(23)15(24)19(20,6)26-17/h7,11,13-15,21,23-25H,1,8-10H2,2-6H3/t11-,13-,14-,15-,17-,18-,19+,20-/m0/s1
InChIKey
WPDITXOBNLYZHH-KAACEJSMSA-N
Chemical Structure
2D Structure
2D structure of Deacetylforskolin
CAS: 64657-20-1
CID: 10044542
Formula: C20H32O6
MW: 368.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight368.5
XLogP30.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Exact Mass368.21988874
Monoisotopic Mass368.21988874
Topological Polar Surface Area107 Ų
Heavy Atom Count26
Formal Charge0
Complexity646
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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