Conantokin G

• Description:

  GluN2B (formally NR2B) selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM) ; also inhibits NMDA-evoked responses in oocytes expressing GluN2B (formally NR2B), but not GluN2A (formally NR2A), subunits (IC50 ~300 nM) . Exhibits neuroprotective properties in vivo and in vitro.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  2264.21

• Molecular Formula:

  C88H138N26O44

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  93438-65-4