[Pro3]-GIP (Mouse)

• Description:

  GIP receptor antagonist (IC50 = 2.6μM) . Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insulin sensitivity, and glucose response to feeding in ob/ob mice.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  4971.62

• Molecular Formula:

  C225H342N62O64S

• Notes:

  Research use only, not for human use.

• Receptor:

  ——