ProTx II

• Description:

  Selective NaV1.7 channel blocker. Shifts activation gating positively and decreases current magnitude. Displays 100-fold selectivity over other sodium channel subtypes.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  3826.59

• Molecular Formula:

  C168H250N46O41S8

• Notes:

  Research use only, not for human use.

• Receptor:

  IC50: 0.3 nM (V1.7), 41 nM (v1.2), 102 nM (V1.3), 39 nM (V1.4), 79 nM (V1.5), 26 nM (V1.6), 146 nM (V1.8)

• CAS Number:

  484598-36-9