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(D-Arg2, Lys4) -Dermorphin (1-4) amide

CAT: 1410-M40130-01Size: 1 EachDry Ice: NoHazardous: No
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Description
DALDA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA shows antinociceptive and respiratory effects.
CAS Number
118476-85-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
611.75
Molecular Formula
C30H45N9O5
Notes
Research use only, not for human use.
Receptor
Other Targets

Chemical Information

Tyrosyl-arginyl-phenylalanyl-lysinamide

dermorphin analog

CAS Number118476-85-0
PubChem CID122222
IUPAC Name(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Molecular FormulaC30H45N9O5
Molecular Weight611.7
XLogP-0.8
Topological Polar Surface Area267
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count8
Rotatable Bond Count19
Heavy Atom Count44
Formal Charge0
Complexity932
SMILES
C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)N
InChI
InChI=1S/C30H45N9O5/c31-15-5-4-9-23(26(33)41)37-29(44)25(18-19-7-2-1-3-8-19)39-28(43)24(10-6-16-36-30(34)35)38-27(42)22(32)17-20-11-13-21(40)14-12-20/h1-3,7-8,11-14,22-25,40H,4-6,9-10,15-18,31-32H2,(H2,33,41)(H,37,44)(H,38,42)(H,39,43)(H4,34,35,36)/t22-,23-,24+,25-/m0/s1
InChIKey
UEVAHGMTRWGMTB-JBXUNAHCSA-N
Chemical Structure
2D Structure
2D structure of Tyrosyl-arginyl-phenylalanyl-lysinamide
CAS: 118476-85-0
CID: 122222
Formula: C30H45N9O5
MW: 611.7
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight611.7
XLogP3-0.8
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count8
Rotatable Bond Count19
Exact Mass611.35436557
Monoisotopic Mass611.35436557
Topological Polar Surface Area267 Ų
Heavy Atom Count44
Formal Charge0
Complexity932
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes