Cortistatin-14

• Description:

  Cortistatin 14 is a neuropeptide expressed in inhibitory neurons of the cerebral cortex. Depresses neuronal activity, and induces slow-wave sleep, likely through antagonism of acetylcholine. It is structurally and functionally similar to somatostatin 14. Competes with somatostatin 14 for binding of somatostatin receptors (IC50s=5, 0.09, 0.3, 0.2, and 0.3nM for receptors sst1-5, respectively) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  1720.03

• Molecular Formula:

  C81H114N20O18S2

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  186901-48-4