12R-LOX-IN-2

• Description:

  12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX) .12R-LOX-IN-2 inhibits imiquimod (IMQ) -induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  271.31

• Molecular Formula:

  C19H13NO

• Notes:

  Research use only, not for human use.

• Receptor:

  Lipoxygenase

• CAS Number:

  3026677-37-9