JC2-11

• Description:

  JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) release from inflammatory vesicles.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  302.3

• Molecular Formula:

  C17H15FO4

• Notes:

  Research use only, not for human use.

• Receptor:

  Dehydrogenase | IL Receptor | AIM2 | ROS | NOD-like Receptor (NLR) | Caspase

• CAS Number:

  937820-89-8