Products for Research Use Only
RegisterLogin

Akt3 degrader 1

CAT: 1410-M36618-01Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M36618-01Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Akt3 degrader 1 is a specific Akt3 degrader with anticancer and antiproliferative activity that inhibits tumor growth in mice.Akt3 degrader 1 is used in the study of non-small cell lung cancer and pancreatic cancer.
CAS Number
2836342-69-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
885.19
Molecular Formula
C53H72N8O4
Notes
Research use only, not for human use.
Receptor
Akt

Chemical Information

Akt3 degrader 1
CAS Number2836342-69-7
PubChem CID165437257
IUPAC NameN-[3-[2-[4-[4-[12-[[2-(1-adamantyl)acetyl]amino]dodecyl]piperazin-1-yl]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]cyclopropanecarboxamide
Molecular FormulaC53H72N8O4
Molecular Weight885.2
XLogP10.4
Topological Polar Surface Area132
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count22
Heavy Atom Count65
Formal Charge0
Complexity1570
SMILES
CC1=CC(=O)N(C2=NC(=NC=C12)NC3=C(C=C(C=C3)N4CCN(CC4)CCCCCCCCCCCCNC(=O)CC56CC7CC(C5)CC(C7)C6)OC)C8=CC=CC(=C8)NC(=O)C9CC9
InChI
InChI=1S/C53H72N8O4/c1-37-26-49(63)61(44-15-13-14-42(30-44)56-51(64)41-16-17-41)50-45(37)36-55-52(58-50)57-46-19-18-43(31-47(46)65-2)60-24-22-59(23-25-60)21-12-10-8-6-4-3-5-7-9-11-20-54-48(62)35-53-32-38-27-39(33-53)29-40(28-38)34-53/h13-15,18-19,26,30-31,36,38-41H,3-12,16-17,20-25,27-29,32-35H2,1-2H3,(H,54,62)(H,56,64)(H,55,57,58)
InChIKey
KLSALARRZCZNDM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Akt3 degrader 1
CAS: 2836342-69-7
CID: 165437257
Formula: C53H72N8O4
MW: 885.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight885.2
XLogP310.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count22
Exact Mass884.56765281
Monoisotopic Mass884.56765281
Topological Polar Surface Area132 Ų
Heavy Atom Count65
Formal Charge0
Complexity1570
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M24048-01WSB1 Degrader 1
M36930-01BLK degrader 1
M21750-01Homo-PROTAC cereblon degrader 1
M24022-01Homo-PROTAC pVHL30 degrader 1
M35183-01PROTAC PD-1/PD-L1 degrader-1
M16955Rpn13 degrader WL40
M13585-01HDAC6 degrader 9c
M13321-01BRD4 degrader AT1
M35146-01ERα degrader-2
M27804-01AKT-I-1

Alternative Products

CatalogName
T74982-01Akt3 degrader 1
HY-175975PROTAC Akt3 Degrader-1
pka-130AKT3
TBI5001-5MGSTING Degrader 1, STING degrader
20R-1478AKT3 antibody
347361-01Akt3 discontinued
7703-100Akt3, Active

Popular Products