USP28-IN-4

• Description:

  USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 μM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorectal and lung squamous carcinoma cells and dose-dependently downregulates c-Myc cellular levels through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  461.36

• Molecular Formula:

  C22H18Cl2N2O3S

• Notes:

  Research use only, not for human use.

• Receptor:

  DUB

• CAS Number:

  2931509-15-6