YX-2-107

• Description:

  YX-2-107 is a selective and potent CDK6-degrading PROTAC with an IC50 value of 4.4 nM.YX-2-107 inhibits RB phosphorylation and FOXM1 expression in vitro, and inhibits the development of Ph+ ALL in rats.YX-2-107 can be used for the prophylaxis and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) . YX-2-107 can be used for the prevention and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  889.95

• Molecular Formula:

  C45H51N11O9

• Notes:

  Research use only, not for human use.

• Receptor:

  PROTACs | CDK

• CAS Number:

  2417408-46-7