PROTAC-O4I2

• Description:

  PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM. PROTAC-O4I2 induced apoptosis in K562 WT cells.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  609.1

• Molecular Formula:

  C29H29ClN6O5S

• Notes:

  Research use only, not for human use.

• Receptor:

  PROTACs | Apoptosis

• CAS Number:

  2785323-62-6