AT-533

• Description:

  AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, including Erk1/2, FAK, Akt/mTOR/p70S6K, . AT-533 inhibits the cell migration, invasion, and the tube formation of human umbilical vein endothelial cells (HUVECs) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  410.51

• Molecular Formula:

  C23H30N4O3

• Notes:

  Research use only, not for human use.

• Receptor:

  HSP | HSV

• CAS Number:

  908112-37-8