KRAS-533

CAT: 1568-C03629-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:1568-C03629-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

10161-87-2

SKU

C03629-5mg

Target

Ras

Applications

Apoptosis

Additionnal Information

KRAS-533 is a potent agonist of KRAS that binds to the GTP/GDP-binding pocket and prevents the hydrolysis of GTP, leading to accumulation of active GTP-bound KRAS. This triggers both apoptotic and autophagic cell death pathways in cancer cells, leading to potent suppression of mutant KRAS lung cancer in vitro and in animal models.

Related Products

Catalog	Name
C01681-01	LY3537982 (KRAS G12C inhibitor 19)
C14511-01	CB-5339

Alternative Products

Catalog	Name
MF-0063398-01	AT-533
BA5773-10	KRA-533
HY-160696	ORIC-533
MF-0145572-01	NB-533
A24155-10	AT-533 10mg
A24155-5	AT-533 5mg
A24155-50	AT-533 50mg
A24155-100	AT-533 100mg
HY-W953639	CRBN ligand-533

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