Products for Research Use Only

Dynamin IN-2

CAT: 1410-M35809-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M35809-02Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM) . Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM) .
CAS Number
1345853-49-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
364.87
Molecular Formula
C22H21ClN2O
Notes
Research use only, not for human use.
Receptor
Dynamin

Chemical Information

Dynamin IN-2
CAS Number1345853-49-7
PubChem CID166642487
IUPAC Name1-carbazol-9-yl-3-[(4-chlorophenyl)methylamino]propan-2-ol
Molecular FormulaC22H21ClN2O
Molecular Weight364.9
XLogP4.3
Topological Polar Surface Area37.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count6
Heavy Atom Count26
Formal Charge0
Complexity418
SMILES
C1=CC=C2C(=C1)C3=CC=CC=C3N2CC(CNCC4=CC=C(C=C4)Cl)O
InChI
InChI=1S/C22H21ClN2O/c23-17-11-9-16(10-12-17)13-24-14-18(26)15-25-21-7-3-1-5-19(21)20-6-2-4-8-22(20)25/h1-12,18,24,26H,13-15H2
InChIKey
AEKXFKTYWDQZGU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dynamin IN-2
CAS: 1345853-49-7
CID: 166642487
Formula: C22H21ClN2O
MW: 364.9
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight364.9
XLogP34.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count6
Exact Mass364.1342410
Monoisotopic Mass364.1342410
Topological Polar Surface Area37.2 Ų
Heavy Atom Count26
Formal Charge0
Complexity418
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes