DIF-3

• Description:

  DIF-3 is a chemical compound that acts by activating GSK-3β to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. This compound exerts a potent antiproliferative effect on the HeLa human cervical cancer cell line by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  272.72

• Molecular Formula:

  C13H17ClO4

• Notes:

  Research use only, not for human use.

• Receptor:

  Wnt/beta-catenin | GSK-3 | CDK

• CAS Number:

  113411-17-9