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JAK2-IN-6

CAT: 1410-M35208-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M35208-01Size:1 Each
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Description
JAK2-IN-6, a polysubstituted aminothiazole derivative, is a potent and selective inhibitor of JAK2 (ic50 at 22.86 μg/mL) . Jak2-in-6 inhibits the activity of JAK2 enzymes by interfering with Jak2-related signaling pathways, thereby producing therapeutic effects on the specific disease IN which JAK2 is dysregulated, and does not show activity on JAK1 and JAK3. JAK2 is a protein involved in signaling pathways that regulate cell growth and division. Abnormal activation of JAK2 has been linked to a variety of diseases, including some types of cancer and inflammatory diseases. JAK2-IN-6 has antiproliferative activity against cancer cells.
CAS Number
353512-04-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
335.83
Molecular Formula
C14H10ClN3OS2
Notes
Research use only, not for human use.
Receptor
JAK

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