SR-0813

CAT: 1410-M35189-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M35189-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR-0813 is a potent and selective inhibitor of the YEATS domain in ENL/AF9, with an IC50 of 25 nM and EC50 of 205 nM for the ENL YEATS domain, and an IC50 of 311 nM and EC50 of 76 nM (CETSA) for the AF9 YEATS domain. It shows over 100-fold lower affinity for MAP3K19 (Kd = 3.5 μM) compared to ENL YEATS (Kd = 30 nM) . SR-0813 can be utilized in acute leukemia research.
CAS Number
2597186-19-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
496.62
Molecular Formula
C25H32N6O3S
Notes
Research use only, not for human use.
Receptor
Epigenetic Reader Domain

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