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Cotosudil

CAT: 1410-M35056-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M35056-01Size:5 mg
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Description
Cotosudil is a ROCK kinase inhibitor with antihypertensive activity and is used to treat or prevent diseases or conditions caused by cataracts, cardiovascular or neurodegenerative diseases or nerve damage.
CAS Number
1258833-31-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
319.42
Molecular Formula
C16H21N3O2S
Notes
Research use only, not for human use.
Receptor
ROCK

Chemical Information

Cotosudil

Cotosudil is a small molecule drug. The usage of the INN stem '-sudil' in the name indicates that Cotosudil is a Rho protein kinase inhibitor. Cotosudil has a monoisotopic molecular weight of 319.14 Da.

CAS Number1258833-31-6
PubChem CID49847659
IUPAC Name6-[[(2R)-2-methyl-1,4-diazocan-1-yl]sulfonyl]isoquinoline
Molecular FormulaC16H21N3O2S
Molecular Weight319.4
XLogP1.7
Topological Polar Surface Area70.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count22
Formal Charge0
Complexity463
SMILES
C[C@@H]1CNCCCCN1S(=O)(=O)C2=CC3=C(C=C2)C=NC=C3
InChI
InChI=1S/C16H21N3O2S/c1-13-11-17-7-2-3-9-19(13)22(20,21)16-5-4-15-12-18-8-6-14(15)10-16/h4-6,8,10,12-13,17H,2-3,7,9,11H2,1H3/t13-/m1/s1
InChIKey
OIJDBECSPSHUGA-CYBMUJFWSA-N
Chemical Structure
2D Structure
2D structure of Cotosudil
CAS: 1258833-31-6
CID: 49847659
Formula: C16H21N3O2S
MW: 319.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight319.4
XLogP31.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass319.13544809
Monoisotopic Mass319.13544809
Topological Polar Surface Area70.7 Ų
Heavy Atom Count22
Formal Charge0
Complexity463
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19189777-01Cotosudil
A24493-10Cotosudil 10mg
A24493-100Cotosudil 100mg
T71106-01Cotosudil 2HCl
A24493-50Cotosudil 50mg
A24493-5Cotosudil 5mg

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