ML 209

• Description :

  ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay) .1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM) . ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.

• CAS Number :

  1334526-14-5

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  441.52

• Molecular Formula :

  C25H31NO6

• Notes :

  Research use only, not for human use.

• Receptor :

  ROR