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Endosidin-2

CAT: 1410-M34902-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M34902-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1) .Endosidin-2 disrupts protein translocation between the endosomes and plasma membrane, thereby facilitating translocation of proteins to the vesicle for degradation. It also inhibits recirculation of endocytosed transferrin to the plasma membrane in HeLa cells and targets multiple isoforms of mammalian EXO70, leading to dysregulation of exocytosis.Endosidin2 can be used as a tool molecule to study cytosolization.
CAS Number
1839524-44-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
414.17
Molecular Formula
C15H12FIN2O3
Notes
Research use only, not for human use.
Receptor
Others

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