TL12-186

• Description:

  TL12-186 is a Cereblon-dependent kinase degrader that degrades CDK, BTK, FLT3, Aurora and other kinases.TL12-186 inhibits CDK2/cyclin A and CDK9/cyclin T1 with IC50s of 73 and 55 nM, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  931.46

• Molecular Formula:

  C44H51ClN10O9S

• Notes:

  Research use only, not for human use.

• Receptor:

  PROTACs | CDK

• CAS Number:

  2250025-88-6