TAS-119

• Description :

  TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95 nM.TAS-119 has a higher affinity for Aurora A than for Aurora B.TAS-119 exhibits potent antitumor activity and potential antimitotic activity. TAS-119 has potent anti-tumor activity and potential anti-mitotic activity.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  506.36

• Molecular Formula :

  C23H22Cl2FN5O3

• Notes :

  Research use only, not for human use.

• Receptor :

  Aurora Kinase

• CAS Number :

  1453099-83-6