Olorofim

• Description :

  Olorofim (F-901318) is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM), but little inhibitory effect on human DHODH (>100 uM) .Olorofim has good efficacy against a variety of pathogenic filamentous and dimorphic fungi, such as Penicillium spp, P. dermatitidis spp and Fusarium spp.

• CAS Number :

  1928707-56-5

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  498.55

• Molecular Formula :

  C28H27FN6O2

• Notes :

  Research use only, not for human use.

• Receptor :

  Dehydrogenase | Antifungal