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Olorofim

CAT: 1410-M34247-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M34247-01Size:1 Each
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Description
Olorofim (F-901318) is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM), but little inhibitory effect on human DHODH (>100 uM) .Olorofim has good efficacy against a variety of pathogenic filamentous and dimorphic fungi, such as Penicillium spp, P. dermatitidis spp and Fusarium spp.
CAS Number
1928707-56-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
498.55
Molecular Formula
C28H27FN6O2
Notes
Research use only, not for human use.
Receptor
Dehydrogenase | Antifungal

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