BMS 182874

• Description:

  BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  345.42

• Molecular Formula:

  C17H19N3O3S

• Notes:

  Research use only, not for human use.

• Receptor:

  Endothelin Receptor

• CAS Number:

  153042-42-3