BMS 182874

• Description :

  BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.

• CAS Number :

  153042-42-3

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  345.42

• Molecular Formula :

  C17H19N3O3S

• Notes :

  Research use only, not for human use.

• Receptor :

  Endothelin Receptor