PF-4981517

• Description:

  PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4) . The IC 50 values for CYP3A activity are 0.03 μM,17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. PF-4981517 is able to be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug Metabolism.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  456.59

• Molecular Formula:

  C26H32N8

• Notes:

  Research use only, not for human use.

• Receptor:

  P450

• CAS Number:

  1390637-82-7