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3-Deoxyglucosone

CAT: 1410-M33580-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M33580-01Size:1 Each
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Description
3-Deoxyglucosone (3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGEs) .3-Deoxyglucosone inactivates glutathione peroxidase and synergizes with low glucose to enhance GLP-1 secretion.3-Deoxyglucosone is used as a biomarker for diabetes mellitus.3-Deoxyglucosone has been shown to be an inhibitor of GLP-1 secretion in the presence of low glucose. 3-Deoxyglucosone inactivates glutathione oxidase, synergizes with low glucose to enhance GLP-1 secretion, and can be used as a biologic marker for diabetes.
CAS Number
4084-27-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
162.14
Molecular Formula
C6H10O5
Notes
Research use only, not for human use.
Receptor
GPX | Glucagon Receptor