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3-Deoxyglucosone

CAT: 0931-T19117Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T19117Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4084-27-9
Target
GPX, Glucagon Receptor
Related Pathways
Oxidation-Reduction, GPCR/G Protein
Purity
0.95
Bioactivity
3-Deoxyglucosone (3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGEs) .3-Deoxyglucosone inactivates glutathione peroxidase and synergizes with low glucose to enhance GLP-1 secretion.3-Deoxyglucosone is used as a biomarker for diabetes mellitus.3-Deoxyglucosone has been shown to be an inhibitor of GLP-1 secretion in the presence of low glucose. 3-Deoxyglucosone inactivates glutathione oxidase, synergizes with low glucose to enhance GLP-1 secretion, and can be used as a biologic marker for diabetes.
Smiles
[C@H](CC(C=O)=O)([C@@H](CO)O)O
Molecular Formula
C6H10O5
Molecular Weight
162.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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