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SB228357

CAT: 1410-M33493-01Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M33493-01Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
CAS Number
181629-93-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
431.38
Molecular Formula
C22H17F4N3O2
Notes
Research use only, not for human use.
Receptor
5-HT Receptor

Chemical Information

SB 228357

SB 228357 is an indolyl carboxylic acid.

CAS Number181629-93-6
PubChem CID443390
IUPAC NameN-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Molecular FormulaC22H17F4N3O2
Molecular Weight431.4
XLogP4.2
Topological Polar Surface Area54.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Heavy Atom Count31
Formal Charge0
Complexity634
SMILES
COC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC(=CC(=C3)C4=CN=CC=C4)F)C(F)(F)F
InChI
InChI=1S/C22H17F4N3O2/c1-31-20-9-13-4-6-29(19(13)11-18(20)22(24,25)26)21(30)28-17-8-15(7-16(23)10-17)14-3-2-5-27-12-14/h2-3,5,7-12H,4,6H2,1H3,(H,28,30)
InChIKey
RRJLJKRFFRZRAF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of SB 228357
CAS: 181629-93-6
CID: 443390
Formula: C22H17F4N3O2
MW: 431.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight431.4
XLogP34.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass431.12568944
Monoisotopic Mass431.12568944
Topological Polar Surface Area54.5 Ų
Heavy Atom Count31
Formal Charge0
Complexity634
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-103154-01SB228357

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