FX-11

• Description:

  FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2) . FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  350.41

• Molecular Formula:

  C22H22O4

• Notes:

  Research use only, not for human use.

• Receptor:

  Dehydrogenase

• CAS Number:

  213971-34-7