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DSM265

CAT: 1410-M33345-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:1410-M33345-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM) .DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections.
CAS Number
1282041-94-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
415.33
Molecular Formula
C14H12F7N5S
Notes
Research use only, not for human use.
Receptor
Dehydrogenase | Parasite

Chemical Information

Dsm-265

DSM265 has been used in trials studying the prevention and treatment of Malaria.

CAS Number1282041-94-4
PubChem CID51347395
IUPAC Name2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Molecular FormulaC14H12F7N5S
Molecular Weight415.33
XLogP6.5
Topological Polar Surface Area56.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count3
Heavy Atom Count27
Formal Charge0
Complexity566
SMILES
CC1=NC2=NC(=NN2C(=C1)NC3=CC=C(C=C3)S(F)(F)(F)(F)F)C(C)(F)F
InChI
InChI=1S/C14H12F7N5S/c1-8-7-11(26-13(22-8)24-12(25-26)14(2,15)16)23-9-3-5-10(6-4-9)27(17,18,19,20)21/h3-7,23H,1-2H3
InChIKey
OIZSVTOIBNSVOS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dsm-265
CAS: 1282041-94-4
CID: 51347395
Formula: C14H12F7N5S
MW: 415.33
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight415.33
XLogP36.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count3
Exact Mass415.07016371
Monoisotopic Mass415.07016371
Topological Polar Surface Area56.1 Ų
Heavy Atom Count27
Formal Charge0
Complexity566
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA2064-100DSM265
A17069-250DSM265 250mg
A17069-500DSM265 500mg
A17069-10DSM265 10mg
A17069-5DSM265 5mg
A17069-100DSM265 100mg
A17069-50DSM265 50mg
A17069-25DSM265 25mg
A17069-1DSM265 1mg
A17069-10mM-DDSM265 10mM * 1mL in DMSO

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