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Apricitabine

CAT: 1410-M33269-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M33269-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance.
CAS Number
160707-69-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
229.26
Molecular Formula
C8H11N3O3S
Notes
Research use only, not for human use.
Receptor
DNA/RNA Synthesis | HIV Protease

Alternative Products

CatalogName
T14313-01Apricitabine
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KGA70769-01(-) -2'-Deoxy-3'-oxa-4'-thiocytidine (apricitabine)
D245520trans-2'-Deoxy-3'-oxa-4'-thiocytidine (Apricitabine)

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