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AMG-1694

CAT: 1410-M33262-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M33262-01Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG-1694, a potent disruptor of the glucokinase–glucokinase regulatory protein (GK-GKRP) complex, operates by promoting the dissociation of this complex, thereby indirectly enhancing GK enzymatic activity with an IC50 of 7 nM. It effectively normalizes blood glucose levels in various rodent diabetes models and lowers blood glucose specifically in diabetic animals without affecting normoglycemic ones. Additionally, AMG-1694 reverses the GKRP-induced inhibition of GK activity and facilitates GK translocation.
CAS Number
1361217-07-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
533.63
Molecular Formula
C23H30F3N3O4S2
Notes
Research use only, not for human use.
Receptor
Glucokinase

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LEC21707-01AMG 1694
HY-12614-01AMG-1694
A21723-1AMG-1694 1mg
A21723-100AMG-1694 100mg
A21723-25AMG-1694 25mg
A21723-10AMG-1694 10mg
A21723-50AMG-1694 50mg
A21723-5AMG-1694 5mg
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