AMG-1694

CAT: 1410-M33262-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M33262-01Size:1 g
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
AMG-1694, a potent disruptor of the glucokinase–glucokinase regulatory protein (GK-GKRP) complex, operates by promoting the dissociation of this complex, thereby indirectly enhancing GK enzymatic activity with an IC50 of 7 nM. It effectively normalizes blood glucose levels in various rodent diabetes models and lowers blood glucose specifically in diabetic animals without affecting normoglycemic ones. Additionally, AMG-1694 reverses the GKRP-induced inhibition of GK activity and facilitates GK translocation.
CAS Number
1361217-07-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
533.63
Molecular Formula
C23H30F3N3O4S2
Notes
Research use only, not for human use.
Receptor
Glucokinase

Popular Products