Products for Research Use Only

RV01

CAT: 1410-M33113-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M33113-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduces iNOS expression and has anti-neuroinflammatory effects. rV01 reduces tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) mRNA levels and secretion. RV01 reduced tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) mRNA levels and secretion, inhibited lps-induced ROS production and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation, decreased toll-like receptor 4 (TLR4) protein expression, and inhibited lps-induced activation of mitogen-activated protein kinase (MAPK) and nuclear transcription factor-кB (NF-кB) signaling pathways.
CAS Number
1016897-10-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
263.29
Molecular Formula
C17H13NO2
Notes
Research use only, not for human use.
Receptor
MAPK | TLR | Dehydrogenase | NF-κB