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RV01

CAT: 0931-T12781-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T12781-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1016897-10-1
Target
TLR, MAPK, NF-κB, Dehydrogenase
Related Pathways
Metabolism, MAPK, NF-κB, Immunology/Inflammation
Purity
0.9993
Bioactivity
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduces iNOS expression and has anti-neuroinflammatory effects. rV01 reduces tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) mRNA levels and secretion. RV01 reduced tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) mRNA levels and secretion, inhibited lps-induced ROS production and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation, decreased toll-like receptor 4 (TLR4) protein expression, and inhibited lps-induced activation of mitogen-activated protein kinase (MAPK) and nuclear transcription factor-кB (NF-кB) signaling pathways.
Smiles
Oc1cc(O)cc(\C=C\c2ccnc3ccccc23)c1
Molecular Formula
C17H13NO2
Molecular Weight
263.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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BA7150-25RV01
A19104-100RV01 100mg
A19104-10RV01 10mg
A19104-200RV01 200mg
A19104-50RV01 50mg
A19104-25RV01 25mg
A19104-5RV01 5mg
A19104-1RV01 1mg
A19104-10mM-DRV01 10mM * 1mL in DMSO

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