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GNF-6231

CAT: 1410-M32943-06Size: 50 mgDry Ice: NoHazardous: No
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CAT#:1410-M32943-06Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.
CAS Number
1243245-18-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
448.49
Molecular Formula
C24H25FN6O2
Notes
Research use only, not for human use.
Receptor
Porcupine

Chemical Information

Gnf6231

a porcupine inhibitor

CAS Number1243245-18-2
PubChem CID46927297
IUPAC NameN-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-fluoro-4-pyridinyl)-5-methyl-3-pyridinyl]acetamide
Molecular FormulaC24H25FN6O2
Molecular Weight448.5
XLogP1.7
Topological Polar Surface Area91.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count33
Formal Charge0
Complexity673
SMILES
CC1=CC(=CN=C1C2=CC(=NC=C2)F)CC(=O)NC3=NC=C(C=C3)N4CCN(CC4)C(=O)C
InChI
InChI=1S/C24H25FN6O2/c1-16-11-18(14-28-24(16)19-5-6-26-21(25)13-19)12-23(33)29-22-4-3-20(15-27-22)31-9-7-30(8-10-31)17(2)32/h3-6,11,13-15H,7-10,12H2,1-2H3,(H,27,29,33)
InChIKey
AXXNRMISICMFNS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Gnf6231
CAS: 1243245-18-2
CID: 46927297
Formula: C24H25FN6O2
MW: 448.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight448.5
XLogP31.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass448.20230222
Monoisotopic Mass448.20230222
Topological Polar Surface Area91.3 Ų
Heavy Atom Count33
Formal Charge0
Complexity673
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BUP11510-01GNF-6231
A16849-25GNF-6231 25mg
A16849-50GNF-6231 50mg
A16849-10GNF-6231 10mg
A16849-5GNF-6231 5mg
HY-100408RGNF-6231 (Standard)
A16849-100GNF-6231 100mg
A16849-2GNF-6231 2mg
A16849-10mM-DGNF-6231 10mM * 1mL in DMSO
GTR19274854-01JNJ-6231

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