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Tuvusertib

CAT: 1410-M32792-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M32792-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
CAS Number
1613200-51-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
370.32
Molecular Formula
C16H12F2N8O
Notes
Research use only, not for human use.
Receptor
Chk | ATM/ATR | Apoptosis

Alternative Products

CatalogName
E1411-01Tuvusertib

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