Products for Research Use Only
RegisterLogin

MF-766

CAT: 1410-M28808-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M28808-02Size:1 mL x 10 mM in DMSO
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay. It can be used for cancer and inflammation diseases research.
CAS Number
1050656-06-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
478.46
Molecular Formula
C27H21F3N2O3
Notes
Research use only, not for human use.
Receptor
FFA1/GPR40

Chemical Information

4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-carboxamido)cyclopropyl)benzoic acid
CAS Number1050656-06-8
PubChem CID25003075
IUPAC Name4-[1-[[1-[[4-(trifluoromethyl)phenyl]methyl]indole-7-carbonyl]amino]cyclopropyl]benzoic acid
Molecular FormulaC27H21F3N2O3
Molecular Weight478.5
XLogP5.1
Topological Polar Surface Area71.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count35
Formal Charge0
Complexity783
SMILES
C1CC1(C2=CC=C(C=C2)C(=O)O)NC(=O)C3=CC=CC4=C3N(C=C4)CC5=CC=C(C=C5)C(F)(F)F
InChI
InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)
InChIKey
BWXAZFCPGFKANL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-carboxamido)cyclopropyl)benzoic acid
CAS: 1050656-06-8
CID: 25003075
Formula: C27H21F3N2O3
MW: 478.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight478.5
XLogP35.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass478.15042702
Monoisotopic Mass478.15042702
Topological Polar Surface Area71.3 Ų
Heavy Atom Count35
Formal Charge0
Complexity783
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M22502-01MF-438
M13591-01MF-094
M14064-01BIO-7662

Alternative Products

CatalogName
BA5704-5MF-766
BA8117-5TRC-766
GTR19222714-01UL-766
E1573-01ARV-766
HY-123251DB-766
T88123-01UMM-766

Popular Products