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4SC-203

CAT: 1410-M28711-05Size: 50 mgDry Ice: NoHazardous: No
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CAT#:1410-M28711-05Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs) .
CAS Number
895533-09-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1283.53
Molecular Formula
C66H74N16O8S2
Notes
Research use only, not for human use.
Receptor
——

Chemical Information

4Sc-203

4SC-203 has been used in trials studying the treatment of Acute Myeloid Leukemia.

CAS Number895533-09-2
PubChem CID44467821
IUPAC Name1-(2-methoxy-5-methylphenyl)-3-[6-[[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl]amino]-1,3-benzothiazol-2-yl]urea
Molecular FormulaC33H38N8O4S
Molecular Weight642.8
XLogP5.3
Topological Polar Surface Area154
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count11
Rotatable Bond Count11
Heavy Atom Count46
Formal Charge0
Complexity963
SMILES
CC1=CC(=C(C=C1)OC)NC(=O)NC2=NC3=C(S2)C=C(C=C3)NC4=NC=NC5=CC(=C(C=C54)OC)OCCCN6CCN(CC6)C
InChI
InChI=1S/C33H38N8O4S/c1-21-6-9-27(43-3)26(16-21)37-32(42)39-33-38-24-8-7-22(17-30(24)46-33)36-31-23-18-28(44-4)29(19-25(23)34-20-35-31)45-15-5-10-41-13-11-40(2)12-14-41/h6-9,16-20H,5,10-15H2,1-4H3,(H,34,35,36)(H2,37,38,39,42)
InChIKey
MAFACRSJGNJHCF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4Sc-203
CAS: 895533-09-2
CID: 44467821
Formula: C33H38N8O4S
MW: 642.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight642.8
XLogP35.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count11
Rotatable Bond Count11
Exact Mass642.27367290
Monoisotopic Mass642.27367290
Topological Polar Surface Area154 Ų
Heavy Atom Count46
Formal Charge0
Complexity963
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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