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NBI-31772

CAT: 1410-M28583-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M28583-02Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NBI-31772 is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM) . NBI-31772 can be used in research on IGF-responsive diseases.
CAS Number
374620-70-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
341.275
Molecular Formula
C17H11NO7
Notes
Research use only, not for human use.
Receptor
——

Chemical Information

Nbi-31772

NBI-31772 is an isoquinoline substituted by 3,4-dihydroxybenzoyl, carboxy, hydroxy, and hydroxy groups at positions 1, 3, 6, and 7, respectively. It is a potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP). It has a role as an insulin-like growth factor-binding protein inhibitor. It is a member of isoquinolines, a member of benzenediols, a tetrol, a hydroxy monocarboxylic acid and an aromatic ketone.

CAS Number374620-70-9
PubChem CID135543997
IUPAC Name1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid
Molecular FormulaC17H11NO7
Molecular Weight341.27
XLogP2.2
Topological Polar Surface Area148
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Heavy Atom Count25
Formal Charge0
Complexity527
SMILES
C1=CC(=C(C=C1C(=O)C2=NC(=CC3=CC(=C(C=C32)O)O)C(=O)O)O)O
InChI
InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)
InChIKey
ZCMFEWUYBFMLIN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Nbi-31772
CAS: 374620-70-9
CID: 135543997
Formula: C17H11NO7
MW: 341.27
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight341.27
XLogP32.2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass341.05355169
Monoisotopic Mass341.05355169
Topological Polar Surface Area148 Ų
Heavy Atom Count25
Formal Charge0
Complexity527
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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