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8-Hydroxy-2'-deoxyguanosine

CAT: 1410-M28576-01Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M28576-01Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8-Oxo-dG is a good biomarker for risk assessment of various cancers and degenerative diseases.
CAS Number
88847-89-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
283.244
Molecular Formula
C10H13N5O5
Notes
Research use only, not for human use.
Receptor
Amino Acids and Derivatives

Chemical Information

8-Hydroxy-2'-Deoxyguanosine

8-hydroxy-2'-deoxyguanosine is guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage. It has a role as a biomarker.

CAS Number88847-89-6
PubChem CID135440064
IUPAC Name2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,7-dihydropurine-6,8-dione
Molecular FormulaC10H13N5O5
Molecular Weight283.24
XLogP-2.6
Topological Polar Surface Area150
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity544
SMILES
C1[C@@H]([C@H](O[C@H]1N2C3=C(C(=O)NC(=N3)N)NC2=O)CO)O
InChI
InChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1
InChIKey
HCAJQHYUCKICQH-VPENINKCSA-N
Chemical Structure
2D Structure
2D structure of 8-Hydroxy-2'-Deoxyguanosine
CAS: 88847-89-6
CID: 135440064
Formula: C10H13N5O5
MW: 283.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight283.24
XLogP3-2.6
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass283.09166853
Monoisotopic Mass283.09166853
Topological Polar Surface Area150 Ų
Heavy Atom Count20
Formal Charge0
Complexity544
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
2177-18-Hydroxy-2'-deoxyguanosine
MBS6046902-018-Oxo-2'-deoxyguanosine (8-Hydroxy-2'-deoxyguanosine)
sc-291736B8-Hydroxy-2′-deoxyguanosine
HY-W011540R-018-Hydroxy-2'-deoxyguanosine (Standard)
HY-W011540S8-Hydroxy-2'-deoxyguanosine-15N5
HY-152367-018-Hydroxy-3'-deoxyguanosine
H9042-248-Hydroxy-2’-deoxyguanosine (8-oxo-dG)
C15300-20uL8-Hydroxy-2'-deoxyguanosine Antibody [K11E8]
O82328-Oxo-2’-deoxyguanosine_x000B__x000B_ (8-Hydroxy-2’-deoxyguanosine)
HY-W6539168-Hydroxy-2'-deoxyguanosine-13C,15N2

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