8-Hydroxy-3'-deoxyguanosine

8-Hydroxy-3'-deoxyguanosine

• UNSPSC Description: 8-Hydroxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/8-hydroxy-3-deoxyguanosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1C[C@@H](CO)O[C@H]1N2C(O)=NC3=C2N=C(N)NC3=O
• Molecular Weight: 283.24
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported