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CAY10781

CAT: 1410-M28128-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M28128-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
CAS Number
1210360-87-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
231.211
Molecular Formula
C11H9N3O3
Notes
Research use only, not for human use.
Receptor
Neutral sphingomyelinase

Chemical Information

2-(6-Oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid
CAS Number1210360-87-4
PubChem CID45490125
IUPAC Name2-(6-oxo-2-pyridin-3-yl-1H-pyrimidin-5-yl)acetic acid
Molecular FormulaC11H9N3O3
Molecular Weight231.21
XLogP-0.7
Topological Polar Surface Area91.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count17
Formal Charge0
Complexity401
SMILES
C1=CC(=CN=C1)C2=NC=C(C(=O)N2)CC(=O)O
InChI
InChI=1S/C11H9N3O3/c15-9(16)4-8-6-13-10(14-11(8)17)7-2-1-3-12-5-7/h1-3,5-6H,4H2,(H,15,16)(H,13,14,17)
InChIKey
PQXHMOPMDOFJHD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(6-Oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid
CAS: 1210360-87-4
CID: 45490125
Formula: C11H9N3O3
MW: 231.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight231.21
XLogP3-0.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass231.06439116
Monoisotopic Mass231.06439116
Topological Polar Surface Area91.7 Ų
Heavy Atom Count17
Formal Charge0
Complexity401
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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