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GDC0575 monohydrochloride

CAT: 1410-M27878-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:1410-M27878-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GDC-0575 is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.
CAS Number
1196504-54-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
414.73
Molecular Formula
C16H21BrClN5O
Notes
Research use only, not for human use.
Receptor
HSGLT2

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