Products for Research Use Only

TASIN-1 Hydrochloride

CAT: 1410-M27797-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M27797-01Size:5 mg
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Description
TASIN-1 Hydrochloride is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
CAS Number
1678515-13-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
388.95
Molecular Formula
C18H29ClN2O3S
Notes
Research use only, not for human use.
Receptor
Ca (2+) receptor

Chemical Information

TASIN-1 Hydrochloride
CAS Number1678515-13-3
PubChem CID132470901
IUPAC Name1-[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]-4-methylpiperidine;hydrochloride
Molecular FormulaC18H29ClN2O3S
Molecular Weight389.0
Topological Polar Surface Area58.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity481
SMILES
CC1CCN(CC1)C2CCN(CC2)S(=O)(=O)C3=CC=C(C=C3)OC.Cl
InChI
InChI=1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)16-9-13-20(14-10-16)24(21,22)18-5-3-17(23-2)4-6-18;/h3-6,15-16H,7-14H2,1-2H3;1H
InChIKey
TXDTUQPRRXNCLP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of TASIN-1 Hydrochloride
CAS: 1678515-13-3
CID: 132470901
Formula: C18H29ClN2O3S
MW: 389.0
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight389.0
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass388.1587417
Monoisotopic Mass388.1587417
Topological Polar Surface Area58.2 Ų
Heavy Atom Count25
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes