Hoechst 34580

• Description:

  Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.Hoechst 34580 is a good candidate for treating Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  451.57

• Molecular Formula:

  C27H29N7

• Notes:

  Research use only, not for human use.

• Receptor:

  Amyloid-β

• CAS Number:

  23555-00-2