AMG 487

• Description :

  AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively.

• CAS Number :

  473719-41-4

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  603.59

• Molecular Formula :

  C32H28F3N5O4

• Notes :

  Research use only, not for human use.

• Receptor :

  CXCR3