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Fz7-21

CAT: 1410-M22723-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M22723-01Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM) .
CAS Number
2247635-23-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1796.05
Molecular Formula
C83H114N18O23S2
Notes
Research use only, not for human use.
Receptor
Human FZD7 CRD|mouse FZD7 CRD

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