Fz7-21

• Description:

  Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  1796.05

• Molecular Formula:

  C83H114N18O23S2

• Notes:

  Research use only, not for human use.

• Receptor:

  Human FZD7 CRD|mouse FZD7 CRD

• CAS Number:

  2247635-23-8